Physical Terms, Physiologic Order & Neuro-anatomic Sequencing
A medical condition is defined as a physiologic variance from a normal range. This is why physiology is the
organizing principle of the medical model.
The Gold Standard In Medical Practice: Physiologic Measures and Reasoning Before Medical Treatment
Different physiologies respond to different treatment. Physical measurement is necessary to determine the presence
and nature of a physiologic abnormality and select a medical therapy that is likely to improve it. Measuring physiology
before and with medical treatment is the way to personalize therapy and achieve a favorable clinical outcome.
Unfortunately the psychiatric model remains based primarily on symptoms and behaviors. These are sorted and classified
by a list of syndromes called DSM disorders. Psychiatrists use interviews, rating scales and performance measures to describe
a patients behavioral syndrome and as the basis for selection of medical treatment. However, clinical experience makes obvious
that there is no consistent relation between these symptoms and behaviors and response to medications. A set of symptoms and
behaviors may suggest a mental disturbance, but does not specify the nature of a person's neurophysiology nor their likely
response to neuro-active agents.
Lacking a measure of individual brain function in these disorders, psychiatric medication selection remains educated guessing
and medication response a chance occurrence. This explains the low rates of treatment outcomes and high rates of adverse effects
that are observed in psychiatry.
To improve the random nature of psychiatric therapeutics, our lab began electroencephalographic (EEG) and quantitative EEG (QEEG)
research in 1986. The goal was to distinguish individual differences in brain function that could help improve medical treatment in
persons with mental disorders. This innovative research generated an inclusive medical approach that draws upon homeostasis - the
established organizing principle of complex physiology - and uses EEG/QEEG data to assist doctors in understanding, separating and
improving brain variations which cause physical illnesses and mental disorders.
In this procedure, a prospective patient's EEG data is compared with a large, clinical outcome database of heterogeneous EEG's and
their diverse medication responses. The patient's EEG data are mathematically classified and correlated with neuro-active medication(s)
likely to improve their neurophysiology.
Research with EEG-linked fMRI has recently shown that the human brain is primarily a homeostatic organ and has increased interest in the
automatic neurophysiology which controls these continuous, stabilizing activities. A breakthrough in neuroscience, this insight has decreased
interest in "lesion behavior" research and accelerated the study of resting state brain activity. It follows that a new clinical approach
is needed which is also grounded in homeostatic physiology.
The psychiatric model isn't based on these complex, instinctive interactions. A similarly oriented clinical approach is needed, one that is
grounded in resting state physiology, gives priority to instinctive brain and bodily interactions and provides a safe, inexpensive technology
for measuring and monitoring them. This is the way to unify human physiology and medical treatment.
My growing EEG/QEEG database includes patients with a broad range of medical diagnoses and/or DSM disorders. I enjoy collaborating with other
physicians and institutions to integrate my research and approach into the practice of general internal and family medicine. Working in partnership
allows us to more effectively diagnose and treat patients.